The FDA recently approved self-collected high-risk human papillomavirus (hrHPV) testing in a health care setting for routine cervical cancer screening (CCS) when cervical specimens can’t otherwise be obtained. This is not for follow-up of abnormal test results or symptoms requiring diagnostic evaluation.
We may release more guidelines and will update you as more information becomes available.
Patient eligibility for self-collection
- Only ages 30–64 years for routine cervical cancer screening
- No symptoms of abnormal bleeding, no active menstrual bleeding or use of vaginal products within 2 days
- Not HIV positive
- No history of cervical cancer
- Asymptomatic and eligible for primary HPV testing
View American College of Obstetricians and Gynecologists guidelines for more information.
Tips for hrHPV self-collection testing
- Check with your lab provider to see if the FDA-approved self-collection kits are available
- Use CPT® code 87624 or 87626 for the FDA-approved HPV screening to meet CCS HEDIS® compliance and close quality gaps
- Must occur during the current measurement year or 4 years prior
- If we’re the secondary payer, you’ll need to submit a secondary claim to us to close the gap
Guidance for hrHPV self-collected routine CCS test results
- HPV negative – Repeat screening in 3 years
- HPV 16 or HPV 18 detected – Refer or return visit for colposcopy
- HPV types 56/59/66 detected with extended genotyping – Retest in 1 year at clinician’s discretion
- Other HPV detected with extended (or without) extended genotyping – Return visit for clinician-collected cervical specimen for cytology or dual stain
Resources
American Cancer Society hrHPV self-collected guidelines
UnitedHealthcare PATH guidelines
National Cancer Institute self-collection for hrHPV testing to prevent CCS guidelines