Beginning Sept. 1, 2026, we’ll be updating our Medical Benefit Therapeutic Equivalent Medications – Excluded Drugs – Commercial Medical Benefit Drug Policy to exclude certain injectable oncology medications (non-preferred) when therapeutically equivalent alternatives are available. Prior authorizations will continue to be required for both non-preferred and alternative drugs.
This change is to help reduce overall health care costs for our members while still offering coverage for a drug with similar efficacy and safety as the non-preferred drug and applies to UnitedHealthcare commercial plans, fully insured and ASO, where summary plan description language allows pharmaceutical product exclusions.
Members may continue to get an excluded drug until current authorization expires or eligibility changes. When the current authorization expires, the provider needs to transition the member to one of the covered medications in the respective therapeutic class.
We define therapeutic equivalence as having essentially the same efficacy and adverse effect profile to another covered medication/product. The following chart lists the injectable oncology medications that will be excluded from medical benefit coverage and the approved alternative:
| Excluded/Non-preferred drugs | Alternative therapeutically equivalent product |
|---|---|
| J0185 Cinvanti® (aprepitant) | J1453 Emend/fosaprepitant (generic) |
| J1434 Focinvez® (fosaprepitant) | J1453 Emend/fosaprepitant (generic) |
| J2468 Posfrea® (palonosetron) | J2469 palonosetron (generic) |
| J9054 Boruzu™ (bortezomib) | J9051, J9049, J9041 bortezomib (generic) |
| J9072 Frindovyx® (cyclophosphamide) | J9073, J9071, J9075 cyclophosphamide (generic) |
| J9074 cyclophosphamide (generic/Sandoz) | J9073, J9071, J9075 cyclophosphamide (generic) |
| J9076 cyclophosphamide (generic/Baxter) | J9073, J9071, J9075 cyclophosphamide (generic) |
| J9172 Docivyx® (docetaxel) | J9171 docetaxel (generic) |
| J9292 Axtle® (pemetrexed) | J9305, J9314, J9322, J9323, J9296, J9294, J9297 pemetrexed (generic) |
| J9304 Pemfexy® (pemetrexed) | J9305, J9314, J9322, J9323, J9296, J9294, J9297 pemetrexed (generic) |
| J9324 Pemrydi RTU® (pemetrexed) | J9305, J9314, J9322, J9323, J9296, J9294, J9297 pemetrexed (generic) |
| J9999 Avgemsi™ (gemcitabine) | J9201, J9196 gemcitabine (generic) |
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PCA-1-26-00358-Clinical-NN_05052026